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Pharmaceutical Grade PVPP

Product Name:Crospovidone
 
Chemical Description:Croslinked PVP,Crospovidone,Insoluble PVP,Pollyvinylpolypyrrolidone
 
INCI/CTFA:Insoluble PVP
 
Pharmacopeia Name:Crospovidone (Crospovidonum)
 
CAS NO.:9003-39-8,25249-54-1
 
Formula Structure:

9-1.jpg

 
Product Properties: Crospovidone is hygroscopic,insoluble in water and all other common solvents,but it swells rapidly in aqueous solutbition without any gel froms.Its; classified as Crospovidone Type A and Type B according to the different particle size.
 
Applications:In the pharmaceutical industry,Crospovidone are widely used as 1)Disintergrating agent,2)Stabilizer for suspension,3)Moisture Absorbent, 4)Complextant of Polyphenols and Tannin for the extract formulations.
 
Specifications:

Product

Crospovidone Type A

Crospovidone Type B

Appearance

White or yellowish-white powder or flakes

Identifications

Meet ID Tests

Solubility

Practically insoluble in water,in alcohol and in methylene chloride

Water- soluble substances

1.0% max

1.0% max

pH((1% in water)

5.0 –8.0

5.0 –8.0

Loss on Drying

5.0% max.

5.0% max.

Sulphated Ash

0.1% max.

0.1% max.

Nitrogen content

11.0 -12.8 %

11.0 -12.8 %

Impurity A

10 ppm max.

10 ppm max.

Peroxide(As H2O2)

400 ppm max.

1000 ppm max.

Heavy Metal

10 ppm max.

10 ppm max.

Particle Size(μm), ≥80%

50-300

5-50

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BAIDU WellTone
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